Viral Infections

Viral  infections are quite prevalent, most typically seen are the common cold, hepatitis, influenza, measles, rabies, Dengue,  diarrhea, AIDS , polio, smallpox, cold sores and genital herpes, Study of various ways through which viruses affect individuals are specified as viral pathogenesis. The purview of the disease/ infection caused by the virus is its virulence. When a virus invades into the host, the immune system starts producing specific/ impromptu antibodies that binds to the virus thereby neutralizing its virulence or kills them. Presence of such antibodies in blood serum detects if a host has ever been exposed to any given virus in the past. This is possible only with the help of specific tests such as ELISA. Vaccinations protect against diseases, by augmenting the production of antibodies. Monoclonal antibodies, are profoundly specific to a single virus, are typically used for detection in fluorescence microscopy. Additionally, viruses being used as gene vectors in the gene therapy of genetic diseases are also gaining momentum; similarly in phage therapy, use of the bacteriophages to encounter bacterial infections and diseases was effectual. The recent approach of genetically engineered viruses in nanobiotechnology is seen as the novel approach to combat various diseases at the genetic level.

Due to the rampant HCV infection and high insistence for such enhanced and effectual treatments, numerous estimates envisage the global industry for HCV treatment costs $20 billion annually, this decade.

  • Pathogenic viruses
  • Viral diseases and host defences
  • Herpes simplex virus
  • Antiviral therapy
  • Clinical virology

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