Mahmoud El-Hindi
Islamic University of Gaza, Palestine
Title: Antibacterial and Antifungal Potentiality of Water Extract of selected Honey Samples on Some Clinical Isolates
Biography
Biography: Mahmoud El-Hindi
Abstract
The medicinal importance of honey has been documented in the world's oldest medical literatures, and since the ancient times, it has been known to possess antimicrobial property as well as wound-healing activity. The healing property of honey is due to the fact that it offers antibacterial activity, maintains a moist wound condition, and its high viscosity helps to provide a protective barrier to prevent infection. Its immunomodulatory property is relevant to wound repair too. The present study was carried to evaluate antibacterial and antifungal activities of water extract of honey against some selected bacteria and fungi (Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and Candida albicans). Antibacterial activity of the honeys was assayed using the well diffusion method and micro-dilution method (MIC) at different concentrations (200-0.195mg/ml) for bacteria and fungi. The inhibitory potency of the honey from different sources varied on the test organisms and all the test organisms were susceptible to the honey extracts at different concentration. The water extracts of the two honey sample showed powerful antimicrobial activity with the same MIC value 6.25 mg/ml against S .aureus, E. coli, and also showed acceptable degree in control of growth of K. pneumonia, P. aeruginosa and Candida albicans. The well diffusion method showed powerful antimicrobial activity with different value 35, 28, 21, 20 & 17 mm against K. pneumonia, E. coli, S .aureus, P. aeruginosa and C. albicans, respectively. These results were revealed the importance of tested extracts in control of some human pathogenic micro-organisms.