Luminiţa Smaranda Iancu
Ramona Gabriela Ursu “Grigore T. Popa†Iasi University of Medicine and Pharmacy, Romania
Title: Human Papilloma Viruses infections in different studies groups from North-East Romania
Biography
Biography: Luminiţa Smaranda Iancu
Abstract
Since 2009 in the Virology Laboratory of Microbiology Discipline we run Human Papilloma Viruses (HPV) genotyping tests by Linear Array HPV Genotyping test. In the first step we obtained WHO proficiency for our laboratory, after best results that we obtained for a panel with HPV samples. In a country in which the prevalence of endocol cancer is in the first place in Europe (23.9/100.000) we tested more than 500 woman for HPV genotype and our results show that 192/514 (37.4%) patients were positive for HPV (infected with single and with multiple HPV types). Most frequent types were: 16 (10.5%), 53 (5.44%), 51 (5.05%), 52 (4.08%) 18 (2.91%) and 31 (2.73%) (Virol J, 2011). In an other study we test HPV and HIV coinfection: DNA/HPV was detected in 18/40 (45%) of the HIV+ patients, and in 350/992 (35.2%) of the HIV- patients. We detect HIV being a risk factor for acquiring multiple HPV type infections. The eight most common HPV types for women below age 30, HIV+/- were: HPV 16, 18, 31, 51, 58, 68, 6 and 82 respectively (PLOS ONE, 2015). In the last years we were focused to test HPV infection related with different neck and head cancers; till know, even we tested more than 200 samples, we do not find a significant association between HPV and these types of cancers. An interesting cases was related with squamous cell carcinoma of conjunctiva, in which we find that 52 HPV type was involved (Indian J Ophthalmology, 2015).