Waleed M. Al-Momania
Jordan University of Science and Technology, Jordan
Title: Biological activities of lanthanide (III) Nitrate Complexes with N-(2-hydroxynaphthalen-1-yl) methylene) Nicotinohydrazide Schiff Base
Biography
Biography: Waleed M. Al-Momania
Abstract
The field of coordination chemistry has registered a phenomenal growth during last few decades. It is well known that precious metals have been used for medicinal purposes for at least 3500 years. At that time, precious metals were believed to benefit health because of their rarity, but research has now well established the link between medicinal properties of inorganic drugs and specific biological properties. The current study was designed to explain the synthesis and characterization of the lanthanide (III) nitrate complexes with N-(2-hydroxynaphthalen-1-yl) methylene) nicotinohydrazideschiff base and to evaluatethe antibacterial and the antioxidant activities of the schiff base and it's lanthanide ion complexes.Antimicrobial activity of the Lanthanide (III) nitrate complexes with N-(2-hydroxynaphthalen-1-yl) methylene) nicotinohydrazideschiff base was estimated by minimum inhibitory concentration (MIC, µg/mL) using a micro-broth dilution method for different clinical isolates such as Eschereshia coli and Enterococcus faecalis. Our present study has shown that moderate antimicrobial activity exists against both ligand and its complexes. There was no significant difference between Gram-positive and Gram-negative bacteria towards the tested ligand and its complexes. The results obtained herein indicate that the ligand and its complexes havea considerable antibacterial activity