8th Global Summit on Microbiology & Infectious Diseases
Benha University, Egypt
Title: A dramatic response to Albendazole in a case of a large hepatic focal lesion mimicking hepatocellular carcinoma
Biography: Mostafa Elkady
An 81 years old lady, presented with Anorexia and severe epigastric pain for 2 weeks was presented. It was of gradual onset and slowly progressive course, dull aching in character and was associated with vomiting and jaundice. There was no GI bleeding or change in bowl hobbits. There was no history of ascites, or any other abdominal swellings. In addition, there were no constitutional manifestations like night sweat, night fever, Her HBA1C was 5.8%. At presentation, ECG revealed no abnormalities, however, abdominal ultrasound was done and revealed mild bright hepatomegaly with hypoechoic left lobe hepatic focal lesion at segment II, about (7×6.8 cm) with multiple calcifications (hydatid disease??) and chronic calcular cholecystitis with normal spleen and no ascites. Subsequently, AFP and hydatid serology were requested and the results were 1.11 ng/ml and 1/80, respectively. Triphasic C T was also done and revealed a left hepatic lobe segment II hypodense focal lesion (8×7 cm) with no contrast enhanced at all phases of study and calcular gall bladder. The patient received Albendazole and UDCA (t.d.s) for 4 weeks then follow up ultrasound was done and revealed a hypoechoic hepatic focal lesion (10×8.6 cm) with calcifications suggesting hydatid diseases with normal spleen and no ascites, one month later follow up ultrasound was done revealed the same left lobe hepatic focal lesion but measuring (8×6 cm). The patient continued the same treatment and ultrasound revealed decreasing size of the hepatic focal lesion to (7×5 cm) and later on after 6 weeks, it reached (2×2 cm) with decreasing ESR and hydatid serology was negative. The patients in now symptom free and kept on follow up.